Product ID:CIPROFLOXACIN SOLUTION, CILOXAN, 0065-0656-10
MSDS Date:06/27/1991
FSC:6505
NIIN:00N043618
MSDS Number: BSYWL

ALCON LABORATORIES INC

6201 SOUTH FREEWAY
FORT WORTH, TX 76134
US

Emergency Phone: 817-551-4444

Info Phone: 817-551-4444

Cage: 16703

ALCON LABORATORIES INC

FORT WORTH, TX 76134 US

Telephone: 817-551-4444

Cage: 16703

(ORAL,RAT)

Fraction By Weight: 0.35%

OSHA PEL N/K

ACGIH TLV: N/K

ACETIC ACID, SODIUM SALT; (SODIUM ACETATE)

CAS: 127-09-3

RTECS: AJ4300010

Fraction By Weight: 0.03%

OSHA PEL N/K

ACGIH TLV: N/K

ACETIC ACID (SARA III)

CAS: 64-19-7

RTECS: AF1225000

Fraction By Weight: 0.04%

OSHA PEL 10 PPM

ACGIH TLV: 10 PPM;15 PPM STEL

EPA Report Quantity: 5000 LBS

DOT Report Quantity: 5000 LBS

MANNITOL

CAS: 87-78-5

RTECS: OP2050000

Fraction By Weight: 4.6%

OSHA PEL N/K

ACGIH TLV: N/K

ACETIC ACID, (ETHYLENEDINITRILO) TETRA-; (EDTA)

CAS: 60-00-4

RTECS: AH4025000

Fraction By Weight: 0.05%

OSHA PEL N/K

ACGIH TLV: N/K

EPA Report Quantity: 5000 LBS

DOT Report Quantity: 5000 LBS

BAC

Fraction By Weight: 0.006%

OSHA PEL N/K

ACGIH TLV: N/K

LD50 LC50 Mixture:SEE INGREDIENT 1.
Routes of Entry: Inhalation:YES Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:THIS PROD CONFORMS TO FDA REGS &
GUIDELINES FOR AN OPHTHALMIC FORMULATION THAT HAS BEEN EXTENSIVELY
TESTED & DEMONSTRATED TO BE SAFE FOR USE IN EYE & IT IS NOT
EXPECTED TO PRDCE DERMAL IRRIT. EXAGGERA TED OCULAR EXPOS IN
ANIMALS HAS ELICITED MIN-TO-MOD CONJ IRRIT. IMMATURE DOGS EXPOS BY
CIPROFLOXACIN (EFTS OF OVEREXP)
Explanation of Carcinogenicity:NOT RELEVANT
Effects of Overexposure:HLTH HAZ:ORALLY AT DOSAGES OF 30 MG/KG/DAY FOR
4 WKS EXHIBITED MIN TOX IN WT-BEARING JOINTS (ARTHROPATHY). EQUIV
HUMAN EXPOS WOULD REQUIRED INGEST OF 600 ML OF CIPROFLOXACIN
OPHTHALMIC SOLN (CONTENTS OF 30 5ML DROPTAINERS FOR A 20 KG PERS).
RPTD EXPOS TO SOME COMPONENTS OF MIXT MAY LEAD TO DEVEL OF SENSIT.
Medical Cond Aggravated by Exposure:PERSONS KNOWN TO BE SENSITIZED TO
ANY COMPONENT OF THE MIXTURE, OR HAVING SYMPTOMS OF SENSITIZATION
TO THE MIXTURE, SHOULD AVOID EXPOSURE.

First Aid:INHAL:REMOVE TO FRESH AIR. SUPPORT BRTHG (GIVE O2/ARTF RESP)
. SKIN/EYE:REMOVE FROM EXPOS & IMMED FLUSH EXPOS AREA W/COPIOUS
AMTS OF WATER FOR AT LST 15 MINS. INGEST:INFO ON OVERDOSAGE IN
HUMANS IS NOT AVAIL. IN EVENT OF ACUTE OVEREXP, STOM SHOULD BE
EMPTIED BY INDUCING VOMIT/BY GASTRIC LAVAGE & PATIENT CAREFULLY
OBSERVED & GIVEN SUPPORTIVE TREATMENT. IN EXTREME CASES, DIALYSIS
MAY (SUPDAT)

Extinguishing Media:USE EXTINGUISHING MEDIA APPROPRIATE FOR THE
SURROUNDING FIRE CONDITIONS.
Fire Fighting Procedures:USE NIOSH/MSHA APPROVED SCBA & FULL PROTECTIVE
EQUIPMENT .
Unusual Fire/Explosion Hazard:TOXIC GASES PRODUCED: CARBON DIOXIDE,
CARBON MONOXIDE, NITROGEN OXIDES.

Spill Release Procedures:WEAR NIOSH/MSHA APPROVED RESPIRATOR &
CHEMICALLY COMPATIBLE GLOVES. VACUUM OR SWEEP UP SPILLAGE. AVOID
CONTACT. PLACE SPILLAGE IN APPROPRIATE CONTAINER FOR WASTE
DISPOSAL. WASH CONTAMINATED CLOTHING B EFORE REUSE. VENTILATE AREA
& WASH SPILL SITE.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:STORE IN TIGHT CNTNR AS DEFINED IN
U.S. PHARMACOPEIA. MATL SHOULD BE HNDLD & STORED PER LBL & OTHER
INSTRUCTIONS TO ENSURE PRODUCT INTEGRITY.
Other Precautions:AVOID CONT W/EYES, SKIN/CLTHG. AVOID BRTHG DUST/MIST.
DO NOT PERMIT EATING, DRINKING/SMOKING NEAR MATL. THIS PROD DOES
NOT POSE UNREASONABLE RISK TO HLTH & SAFETY/PROPERTY WHEN
TRANSPORTED IN COMMERCE . INFO IN SPECIAL PROT INFO (SUPDAT)

Respiratory Protection:NIOSH/MSHA APPROVED RESPIRATOR.
Ventilation:USE GENERAL OR LOCAL EXHAUST.
Protective Gloves:RUBBER GLOVES.
Eye Protection:ANSI APPRVD CHEM WORKER GOGGLES .
Other Protective Equipment:APPROPRIATE LABORATORY APPAREL TO PROTECT
EXPOSED SKIN.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
FIRST AID PROC:BE REQD TO REMOVE DRUG (CIPROFLOXACIN) FROM BODY. OTHER
PREC:SECTION ASSUMES LG QTYS OF PROD SUCH AS MIGHT BE ENCOUNTERED
IN WAREHOUSE STORAGE OR AN INDUSTRIAL ACCIDENT.

HCC:N1
Solubility in Water:SOLUBLE
Appearance and Odor:AQUEOUS SOLUTION.

Stability Indicator/Materials to Avoid:YES
NONE OTHER THAN WATER ALONE WOULD PRODUCE.
Stability Condition to Avoid:THIS PRODUCT IS STABLE FROM A SAFETY POINT
OF VIEW.
Hazardous Decomposition Products:WHEN HEATED TO DECOMP, MATL EMITS
TOXIC FUMES. TOXIC GASES PRODUCED:CARBON DIOXIDE, CARBON MONOXIDE,
NITROGEN OXIDES.

Waste Disposal Methods:DISPOSE I/A/W ALL APPLICABLE FEDERAL, STATE &
LOCAL ENVIRONMENTAL REGULATIONS. THIS PRODUCT DOES NOT MEET THE
DEFINITION OF HAZARDOUS WASTE AS DEFINED IN 40 CFR, PART 261.11.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.